WebMar 14, 2016 · Genotoxic Stress and Cancer Unit, Institut Curie, Research Center, Orsay 91405, France; CNRS UMR3348, Centre Universitaire, Orsay 91405, France; ... Institut Curie Centre de Recherche Orsay; Proceedings of the National Academy of Sciences of the United States of America, 14 Mar 2016, 113(13): 3515-3520 WebJan 19, 2024 · Despite progress in therapeutic strategies and understanding of cancer cell biology, there is a large attrition of promising therapeutics into the clinic. One predominant reason is the huge gap between 2D in-vitro assays used for drug screening, and the in-vivo 3D-physiological environment. This is particularly important for a specific category of …
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