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Verapamil hepatic clearance in four preclinical rat models: towards ...
Nettet15. des. 2004 · In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model In vitro studies indicate the therapeutic potential of mTOR inhibitors in treating multiple myeloma. To provide further support for this potential, we used the rapamycin analog CCI-779 in a myeloma xenograft model. Nettet1. apr. 2024 · To rule out whether the abnormal clearance was due to either the unique properties of chimeric αCD30 antibody or the specific biology of the NSG mice, the pharmacokinetic profiles of a humanized IgG1 antibody (αCD70) and an auristatin conjugate (αCD70-mcMMAF) were also assessed in the NOG mice, a highly immune … the court rockbeare exeter
(PDF) PCSK9 acts as a key regulator of Aβ clearance
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