WebMay 8, 2024 · National Center for Biotechnology Information WebPaclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. Brand Names. Abraxane, Taxol. Generic Name Paclitaxel DrugBank Accession Number
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WebRecently, the efficacy of the combination of gemcitabine and nab-paclitaxel for pancreatic ductal adenocarcinoma (PDAC) patients has been reported, however, there is no recommendation for dose and administration to patients undergoing hemodialysis (HD). A 66-year-old man began receiving HD for chronic renal failure 4 years previously. Web•Exposure and toxicity of paclitaxel can be increased in patients with hepatic impairment; therefore administer with caution. (5.4) • ABRAXANE contains albumin derived from human blood which has , a theoretical risk of viral transmission. (5.5) • Fetal harm may occur when administered to a pregnant woman.
WebPaclitaxel is a novel antimicrotubule agent that promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. This stability results in the... Read more Did you find an answer to your question? Yes No WebAug 31, 2024 · Paclitaxel can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
WebJul 6, 2024 · Paclitaxel is a prescription medicine used to treat the symptoms of Cancer of the breast, ovaries, Non- small Cell Lung Cancer, and AIDS-related Kaposi’s Sarcoma … WebPaclitaxel is a novel antimicrotubule agent that promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. This stability …
WebPaclitaxel has been shown to be clastogenic in vitro (chromosome aberrations in human lymphocytes) and in vivo ... There is no known antidote for paclitaxel overdosage. The …
WebDuring paclitaxel treatment, Grade IV neutropenia was reported for 15% of patients, Grade II/III neurosensory toxicity for 15%, Grade II/III myalgias for 23%, and alopecia for 46%. The incidences of severe hematologic toxicities, infections, mucositis, and cardiovascular events increased with higher doses of doxorubicin. subject to change verbiageWebThe goal of antidote administration is to reverse the action of the extravasated agent, interfere with the process of cell destruction, prevent tissue necrosis, or limit the extent of … subject to circumstancesWebSep 21, 2009 · The most common adverse effects included a decreased white blood cell count (72.5%), decreased hemoglobin (42.5%), decreased platelet count (26%), increased aspartate aminotransferase (36.8%), … subject to chennai jurisdictionWebMay 8, 2024 · Paclitaxel is an antimicrotubule agent. It promotes the assembly of microtubules by enhancing the action of tubulin dimers and stabilizing current … subject to collateral attackPaclitaxel is a natural product with antitumor activity. Paclitaxel is obtained via a semi-synthetic process from Taxus baccata .The chemical name for Paclitaxel is 5β,20-Epoxy-1,2α,4,7β, 10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine. … See more Paclitaxel Injection, USP is a clear, colorless to slightly yellow viscous solution. It is supplied as a nonaqueous solution intended for dilution with a suitable parenteral … See more Paclitaxel is a novel antimicrotubule agent that promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing depolymerization. … See more Paclitaxel, USP is a natural product with antitumor activity. Paclitaxel, USP is obtained via a semi-synthetic process from Taxus baccata. The … See more Paclitaxel, USP is a white to off-white crystalline powder with the molecular formula C47H51NO14 and a molecular weight of 853.9. It is highly lipophilic, insoluble in water, and melts at around 216° to 217°C. See more subject to change without further noticeWebAug 30, 2024 · Paclitaxel is a chemotherapy drug used to treat various types of cancers including ovarian cancer, breast cancer, non-small cell lung cancer, and AIDS-related Kaposi sarcoma. Common side effects of paclitaxel include blood disorders, bleeding, infections, injection site reaction, leakage of drug out of the vein (extravasation), skin … pain in your heel when you walkWebMar 27, 2003 · Paclitaxel is a novel anti-neoplastic with a wide spectrum of activity in various malignant tumors. Extravasation of chemotherapy drugs is a widely feared adverse event in oncology patients. subject to cic