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Trupath homes
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WebDec 14, 2024 · TRUPATH uses an updated version of BRET called BRET2. Figure 1: TRUPATH measures heterotrimeric G protein dissociation by bioluminescence resonance energy transfer 2, or BRET2. With binding of the drug, the alpha and beta subunits dissociate resulting in decreased BRET2 signal. With increased concentration of drug, the BRET2 …
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